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Table 2 Distribution of IKZF-1 variants alleles in ALL cases and controls

From: IKZF1 genetic variants rs4132601 and rs11978267 and acute lymphoblastic leukemia risk in Tunisian children: a case-control study

SNP

Position a

Minor Allele

Cases b

Controlsb

HWE

χ2

p c

OR (95% CI)

Power (%)

rs4132601 T/G

50,402,906

G

36%

26%

0.88

< 0.001

0.029

1.54 (1.04–2.28)

78.5

rs11978267 A/G

50,398,606

G

17%

11%

< 0.05

0.283

0.086

1.57(0.93–2.67)

89.5

  1. aLocation on chromosome based on dbSNP build 125
  2. bMinor allele (frequency)
  3. cAdjusted p value, adjusted for age and gender
  4. HWE Hardy-Weinberg Equilibrium
  5. SNP Single Nucleotide Polymorphism
  6. rs4132601 is significant associated with ALL (P<0.05)
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BMC Medical Genetics

ISSN: 1471-2350

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