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Table 4 The frequency of genotypes and alleles of rs3740051 in patients with non-invasive PA and invasive PA

From: SIRT1 (rs3740051) role in pituitary adenoma development

Genotype/alleleFrequency (%)OR** (CI) p value
Non-invasive PA group, N (%) (n = 58)Invasive PA group, N (%) (n = 84)p value*
Genotype
 G/G2 (3.4)0 (0) 
 G/A15 (25.9)7 (8.3)0.003*0.248 (0.094–0.658) 0.005
 A/A41 (70.7)77 (91.7) Reference
Allele
 G19 (16.4)7 (4.2)< 0.001*0.229 (0.091–0.575) 0.002
 A97 (83.6)161 (95.8)  
  1. PA pituitary adenoma, p value significance level, OR odds ratio, CI confidence interval.
  2. *Pearson’s χ 2 test
  3. **Odds ratios were evaluated under the codominant and additive genetic models