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Table 4 Association of SNPs with risk of stroke based on logistic tests adjusted by gender and age

From: Genetic variants in CYP4F2 were significantly correlated with susceptibility to ischemic stroke

SNP-ID Model Genotype No. (frequency) Adjusteda
Case Control OR (95% CI) pb-value
rs3093203 codominant G/G 275 (57.7%) 292 (59.2%) 1.00
A/G 180 (37.7%) 178 (36.1%) 1.07 (0.82–1.41) 0.614
A/A 22 (4.6%) 23 (4.7%) 0.90 (0.48–1.69) 0.737
dominant G/G 275 (57.7%) 292 (59.2%) 1.00
A/G-A/A 202 (42.3%) 201 (40.8%) 1.02 (0.82–1.27) 0.868
recessive G/G-A/G 455 (95.4%) 470 (95.3%) 1.00
A/A 22 (4.6%) 23 (4.7%) 1.05 (0.81–1.37) 0.706
log-additive 0.87 (0.47–1.63) 0.670
rs3093193 codominant C/C 216 (45.3%) 248 (50.2%) 1.00
G/C 213 (44.7%) 208 (42.1%) 1.14 (0.87–1.50) 0.342
G/G 48 (10.01) 38 (7.7%) 1.39 (0.86–2.23) 0.178
dominant C/C 216 (45.3%) 248 (50.2%) 1.00
G/C-G/G 261 (54.7%) 246 (49.8%) 1.16 (0.95–1.42) 0.143
recessive C/C-G/C 429 (89.9%) 456 (92.3%) 1.00
G/G 48 (10.1%) 38 (7.7%) 1.18 (0.91–1.53) 0.214
log-additive 1.30 (0.82–2.05) 0.259
rs12459936 codominant C/C 158 (33.5%) 139 (28.1%) 1.00
T/C 238 (50.5%) 254 (51.4%) 0.89 (0.66–1.19) 0.422
T/T 75 (16.0%) 101 (20.5%) 0.71 (0.48–1.05) 0.082
dominant C/C 158 (33.5%) 139 (28.1%) 1.00
T/C-T/T 313 (66.5%) 355 (61.9%) 0.85 (0.70–1.03) 0.089
recessive C/C-T/C 396 (84.0%) 393 (79.5%) 1.00
T/T 75 (16.0%) 101 (20.5%) 0.84 (0.63–1.11) 0.212
log-additive 0.77 (0.55–1.08) 0.123
rs3093144 codominant C/C 304 (64.0%) 344 (69.5%) 1.00
T/C 153 (32.2%) 140 (28.3%) 1.18 (0.88–1.56) 0.266
T/T 18 (3.8%) 11 (2.2%) 1.95 (0.89–4.28) 0.095
dominant C/C 304 (64.0%) 344 (69.5%) 1.00
T/C-T/T 171 (36.0%) 151 (30.5%) 1.24 (0.98–1.58) 0.075
recessive C/C-T/C 457 (96.2%) 484 (97.8%) 1.00
T/T 18 (3.8%) 11 (2.2%) 1.23 (0.93–1.62) 0.142
log-additive 1.86 (0.85–4.05) 0.120
rs3093110 codominant A/A 364 (76.3%) 378 (76.5%) 1.00
G/A 105 (22.0%) 108 (21.9%) 1.01 (0.74–1.37) 0.977
G/G 8 (1.7%) 8 (1.6%) 1.00 (0.37–2.75) 0.994
dominant A/A 304 (64.0%) 344 (69.5%) 1.00
G/A-G/G 171 (36.0%) 151 (30.5%) 1.00 (0.76–1.32) 0.978
recessive A/A-G/A 469 (98.3%) 486 (98.4%) 1.00
G/G 8 (1.7%) 8 (1.6%) 1.01 (0.74–1.36) 0.977
log-additive 1.00 (0.37–2.74) 0.996
  1. Adjusteda for age and sex in a logistic regression model
  2. pb values were calculated from wald test
  3. p values indicate statistical significance (p < 0.05)