Genetic variants in CYP4F2 were significantly correlated with susceptibility to ischemic stroke

BMC Medical Genetics

Table 3 Basic information of candidate SNPs in CYP4F2 and associations with stroke

SNP-ID	Chr	Gene	Position	Alleles	MAF		p^a-HWE	OR (95% CI)	p^b-value
SNP-ID	Chr	Gene	Position	(minor/major)	cases	controls	p^a-HWE	OR (95% CI)	p^b-value
rs3093203	19	CYP4F2	15,878,374	A/G	0.235	0.227	0.608	1.04 (0.85–1.29)	0.691
rs3093193	19	CYP4F2	15,881,104	G/C	0.324	0.287	0.584	1.19 (0.98–1.44)	0.081
rs12459936	19	CYP4F2	15,882,231	T/C	0.412	0.462	0.470	0.82 (0.68–0.98)	0.028*
rs3093144	19	CYP4F2	15,891,487	T/C	0.199	0.164	0.621	1.27 (1.01–1.60)	0.043*
rs3093110	19	CYP4F2	15,896,974	G/A	0.127	0.126	0.839	1.01 (0.77–1.32)	0.930

SNP single nucleotide polymorphism, MAF: minor allele frequency, HWE Hardy-Weinberg equilibrium, OR odds ratio, 95% CI: 95%confidence interval
p^a-value were calculated from Fisher’s exact test; ^b p values were calculated from two-sided χ² test
*Bold values indicate statistical significance (p < 0.05)

ISSN: 1471-2350