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Table 3 Associations between haplotypes of DGCR8 genes and preeclampsia subtypes a

From: Genetic polymorphism in DGCR8 is associated with late onset of preeclampsia

Haplotype Control EOPE LOPE
freq freq OR(95%CI) p p b freq OR(95%CI) p p b
DGCR8 rs1558496/ rs1640299/ rs720012/ rs720014/ rs9606241
 C G A T G 0.063 0.106 1.74(0.92, 3.30) 0.083 0.415 0.053 0.83 (0.49, 1.42) 0.495 0.495
 T G A C A 0.077 0.045 0.57(0.24, 1.35) 0.195 0.488 0.155 2.20 (1.49, 3.25) 5.90e-5 2.95e-4
 T G A C G 0.084 0.098 1.19 (0.63, 2.25) 0.588 0.597, 0.126 1.58 (1.06, 2.36) 0.024 0.040
 T T A T A 0.198 0.220 1.13 (0.72, 1.78) 0.597 0.597 0.163 0.78 (0.57, 1.08) 0.136 0.170
 T T G T A 0.573 0.530 0.83(0.57, 1.21) 0.339 0.565 0.500 0.74 (0.58, 0.95) 0.018 0.040
  1. aAll those frequency < 0.03 were ignored in analysis;
  2. bFDR adjusted p value;
  3. Abbreviation: EOPE early onset preeclampsia, LOPE late onset preeclampsia