Table 3 Associations between haplotypes of DGCR8 genes and preeclampsia subtypes a
From: Genetic polymorphism in DGCR8 is associated with late onset of preeclampsia
Haplotype | Control | EOPE | LOPE | ||||||
|---|---|---|---|---|---|---|---|---|---|
freq | freq | OR(95%CI) | p | p b | freq | OR(95%CI) | p | p b | |
DGCR8 rs1558496/ rs1640299/ rs720012/ rs720014/ rs9606241 | |||||||||
C G A T G | 0.063 | 0.106 | 1.74(0.92, 3.30) | 0.083 | 0.415 | 0.053 | 0.83 (0.49, 1.42) | 0.495 | 0.495 |
T G A C A | 0.077 | 0.045 | 0.57(0.24, 1.35) | 0.195 | 0.488 | 0.155 | 2.20 (1.49, 3.25) | 5.90e-5 | 2.95e-4 |
T G A C G | 0.084 | 0.098 | 1.19 (0.63, 2.25) | 0.588 | 0.597, | 0.126 | 1.58 (1.06, 2.36) | 0.024 | 0.040 |
T T A T A | 0.198 | 0.220 | 1.13 (0.72, 1.78) | 0.597 | 0.597 | 0.163 | 0.78 (0.57, 1.08) | 0.136 | 0.170 |
T T G T A | 0.573 | 0.530 | 0.83(0.57, 1.21) | 0.339 | 0.565 | 0.500 | 0.74 (0.58, 0.95) | 0.018 | 0.040 |