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Table 3 Descriptive statistics of the breast cancer cohort

From: Novel mutations in actionable breast cancer genes by targeted sequencing in an ethnically homogenous cohort

Description History of study cases (specimen type: blood) % History of study cases (specimen type: tissue) %
Number of samples 43/52 82.69 9/52 17.31
Age range (years)
 30–39 13/43 30.23 3/9 33.33
 40–49 16/43 37.21 3/9 33.33
 50–70 14/43 32.56 3/9 33.33
Clinical information
 Breast Cancer 23/43 53.49 9/9 100.00
  Stage I 5/23 21.74 0/9 0.00
  Stage II 12/23 52.17 5/9 55.55
  Stage III 6/23 26.09 2/9 22.22
  Stage unknown N/A N/A 2/9 22.22
  Grade I 3/23 13.04
  Grade II 13/23 56.52
  Grade III 6/23 26.09
  Grade unknown 1/23 4.35 9/9 100
Breast lump 11/43 25.58
Breast pain and secretion 5/43 11.63
No symptoms 4/43 9.30
Family History
Positive 38/43 88.37 2/9 22.22
Negative 5/43 11.63 3/9 33.33
Unknown 4/9 44.44
Mutation found(including VUS and Pathogenic) 11/43 25.58 3/9
(1 patient carried 2 mutations. So total number of mutations in 3 patients are 4)
33.33
BRCA1(V + P) 4/43 9.30 1/9 33.33
BRCA2(V + P) 6/43 13.95 1/9 33.33
TP53(P) 2/9 22.22
ERBB2(V) 1/43 2.32
  1. Note: V:VUS and P: Pathogenic