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Fig. 1 | BMC Medical Genetics

Fig. 1

From: Metastatic colorectal cancer and severe hypocalcemia following irinotecan administration in a patient with X-linked agammaglobulinemia: a case report

Fig. 1

The timeline, diagnosis and progression focus. a The timeline of hospitalization: This patient was diagnosed with XLA at the age of 4. He suffered upper abdominal pain on Oct 2016, and was diagnosed with advanced colorectal cancer with liver metastasis by liver biopsy ((b), magnification, × 100) and PET-CT scan (c). Abdominal CT scans on Oct 21th 2016 (d) and Jan 9th 2017 (e) showed that the tumor was stabilized after the first two treatment cycles. However, abdominal CT scans on Mar 24th 2017 (f) and May 22th 2017 (g) showed metastatic tumor progressed. Blood calcium/potassium levels (h) and tumor load (i) were recorded throughout all treatment cycles. The dotted lines indicate the starting time of each chemotherapy treatment cycle. The dark dotted line indicates the sixth treatment cycle when oxaliplatin was replaced by irinotecan

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