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Table 4 Impact of MC4R variants rs12970134 and rs17782313 on PCOS using a multinomial logistic regression test

From: MC4R variants rs12970134 and rs17782313 are associated with obese polycystic ovary syndrome patients in the Western region of Saudi Arabia

SNP

Variable

Group

Genotype

B

p-value

OR (95% CI)

rs12970134 a

BMI (kg/m2)

Control (n = 94)

A/G

−0.003

0.935

0.997 (0.921–1.078)

A/A

0.052

0.48

1.053 (0.912–1.216)

Patient (n = 95)

A/G

0.027

0.553

1.027 (0.94–1.122)

A/A

0.298

0.002**

1.348 (1.113–1.631)

rs17782313 b

BMI (kg/m2)

Control (n = 94)

C/T

0.035

0.935

1.035 (0.957–1.12)

C/C

0.102

0.48

1.108 (0.953–1.287)

Patient (n = 95)

C/T

−0.008

0.553

0.992 (0.906–1.086)

C/C

0.311

0.002**

1.364 (1.121–1.661)

  1. aThe reference category is G/G
  2. bThe reference category is T/T
  3. **p < 0.01