Table 3 Association between MC4R variants rs12970134 and rs17782313 and the multiple variables

Variables

p-value

p-value

A/A

A/G

G/G

A/A

A/G

G/G

BMI (kg/m²)

33.5 ± 9.4

24.5 ± 6.8

23.5 ± 6.6

0.003**

23.2 ± 13.8

21.1 ± 5.5

23.1 ± 7.3

0.941

AMH (ng/ml)

5.6 ± 5.6

4.9 ± 5.5

4.7 ± 4.4

0.953

2.2 ± 0.0

2.3 ± 1.9

2.3 ± 1.4

0.482

LH (IU/ml)

9.4 ± 3.4

8.8 ± 8.9

8.3 ± 9.6

0.941

3.4 ± 5.7

6.6 ± 6.2

5.6 ± 5.3

0.224

FSH (IU/ml)

4.6 ± 2.7

5.3 ± 2.9

4.7 ± 2.2

0.300

3.3 ± 4.3

4.6 ± 2.5

4.9 ± 2.6

0.502

LH/FSH ratio

2.1 ± 1.3

2.0 ± 1.6

1.7 ± 1.7

0.926

0.8 ± 1.1

1.7 ± 1.4

1.2 ± 1.3

0.325

Variables

p-value

p-value

C/C

C/T

T/T

C/C

C/T

T/T

BMI (kg/m²)

34.9 ± 6.0

24.1 ± 5.6

23.5 ± 7.1

0.001***

23.6 ± 17.3

21.4 ± 7.0

23 ± 5.8

0.794

AMH (ng/ml)

4.3 ± 5.0

4.9 ± 5.5

4.7 ± 4.5

0.982

2.3 ± 0.0

2.3 ± 1.9

2.3 ± 1.6

0.881

LH (IU/ml)

9.3 ± 6.1

8.8 ± 9.2

8.4 ± 9.6

0.975

4.4 ± 5.9

6.1 ± 6.4

5.6 ± 5.7

0.573

FSH (IU/ml)

4.6 ± 2.4

5.2 ± 2.7

4.8 ± 2.3

0.690

3.8 ± 4.8

4.5 ± 2.8

4.9 ± 2.3

0.573

LH/FSH ratio

1.8 ± 1.6

2.2 ± 1.8

1.7 ± 1.6

0.998

1.0 ± 1.3

1.7 ± 1.4

1.1 ± 1.4

0.367