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Fig. 4 | BMC Medical Genetics

Fig. 4

From: A novel frameshift mutation in the PITX2 gene in a family with Axenfeld-Rieger syndrome using targeted exome sequencing

Fig. 4

The mRNA expression of PITX2 in lymphocytes of the affected individuals and the controls. The mean expression (±SEM) of PITX2 mRNA in affected individuals (n = 3) and controls (n = 3) was measured by quantitative real-time PCR by primers before (PITX2–1) and after (PITX2–2) the mutant site. PITX2–1 columns represent both truncated and full-length pitx2 transcripts, while PITX2–2 columns indicate the full-length PITX2 mRNA. **, p < 0.05; ***, p < 0.01

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BMC Medical Genetics

ISSN: 1471-2350

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