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Table 3 Effects of clinical factors on the risk of hypertension according to mitochondrial ND2. 5178 C > A genotype

From: Interaction between mitochondrial NADH dehydrogenase subunit-2 5178 C > A and clinical risk factors on the susceptibility of essential hypertension in Chinese population

 

ND2. 5178 C carriers (n = 1172)

ND2. 5178 A carriers (n = 466)

ORa (95% CI)

Pa value

ORa (95% CI)

Pa value

Male, n (%)

0.83 (0.54–1.25)

0.37

1.31 (0.63–2.71)

0.47

Age, years

0.99 (0.97–1.01)

0.33

1.00 (0.97–1.03)

0.94

BMI, kg/m2

1.24 (1.18–1.30)

<  0.01

1.19 (1.10–1.29)

<  0.01

Current smokers, n (%)

1.51 (1.11–2.06)

0.01

0.64 (0.39–1.04)

0.07

Current drinkers, n (%)

0.92 (0.67–1.27)

0.63

0.63 (0.38–1.07)

0.09

TC, mmol/l

2.02 (1.26–3.25)

<  0.01

10.59 (3.05–36.79)

<  0.01

TG, mmol/l

1.57 (1.10–2.24)

0.01

0.73 (0.38–1.41)

0.35

  1. OR odds ratio, CI confidence interval, BMI body mass index, TC total cholesterol, TG triglyceride
  2. aAdjusted for age, gender, BMI, smoking, drinking, TC, TG, LDL-C, HDL-C, SCr, BUN and FPG levels