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Table 3 Summary of case control studies of the association of HLA-DRB1 and Abdominal Aortic Aneurysms

From: Genetic polymorphism of HLA-DRB1 alleles in Mexican mestizo patients with abdominal aortic aneurysms

  Author Year of Publication HLA Isotypes and Subtypes Cases/Controls P Value Odds Ratio OR 95% CI
1 Tilson [6] 1996 HLA-DRB1*02   P = 0.037 NR NR
HLA-DRB1*12* 5/NR P = 0.023
2 Rasmussen [21] 1997 HLA-DRB1*15 37/90 p < 0.05 NR NR
HLA-DRB1*0404
3 Hiroshe [15] 1998 HLA-DRB1*2 (15) 46/50 P < 0.005 NR NR
4 Rasmussen [16] 2001 HLA-DRB1*02, 102/118 P = .03 2.2 1.2–4.0;
HLA-DRB1*04 Degenerative P = .01 2.0 1.1–3.7,
HLA-DRB1*02, 40/118   3.7 1.8–8.6;
HLA-DRB1*04 Immflamatory   2.5 1.1–6.1
5 Rasmussen [17] 2002 HLA-DRB1*02, 96/NR NR 2.5 1.4 a 4.3
HLA-DRB1*04    2.1 1.2 a 3.7
6 Monux [18] 2003 HLA-DRB1*04 72/380 P = 0.02 2.59 1.4 a 4.3
7 Sugimoto [19] 2003 HLA-DRB1*1502. 46/40 p < 0.005 NR NR
8 Badger [20] 2007 HLA-DRB1*03, *04, *07, and *15 241/NR NS NR NR
  1. NR Not reported