Table 3 Dysregulated miR-15/107 family in human diseases

Adrenocortical carcinoma

-

-

-

-

-

-

-

-

√

1

Alzheimer's disease

√

-

-

-

√

-

-

-

-

2

Acute lymphoblastic leukemia (ALL)

-

-

-

-

-

-

√

-

-

1

Acute myeloid leukemia (AML)

-

√

-

√

-

√

√

-

-

4

Acute promyelocytic leukemia (APL)

√

√

-

-

-

-

-

-

-

2

Autism spectrum disorder (ASD)

√

√

-

-

-

-

-

-

-

2

B-cell chronic lymphocytic leukemia

-

√

-

-

-

-

-

-

-

1

Bladder cancer

-

-

-

-

-

√

-

-

-

1

Breast cancer

-

-

-

-

-

√

-

√

-

2

Cardiac hypertrophy

-

√

-

√

√

√

√

-

-

5

Cerebellar neurodegeneration

-

-

-

√

-

-

-

-

-

1

Chronic lymphocytic leukemia (CLL)

√

-

√

-

√

√

√

-

-

5

Chronic pancreatitis

-

-

-

-

-

√

-

√

-

2

Colorectal cancer

-

√

-

-

√

√

-

√

-

4

Endometriosis

-

-

-

-

-

-

√

-

-

1

Epithelial ovarian cancer (EOC)

-

-

-

√

-

-

-

-

-

1

Esophageal cancer

-

-

-

√

√

-

-

-

-

2

Gastric cancer (stomach cancer)

-

√

√

√

√

-

-

-

-

4

Glioma

√

√

√

-

-

-

-

-

-

3

Heart failure

-

-

-

-

-

√

-

-

-

1

Head and neck squamous cell carcinoma (HNSCC)

√

-

-

-

-

√

√

-

-

3

Hepatocellular carcinoma (HCC)

√

-

√

-

√

√

-

-

-

4

Hodgkin's lymphoma

-

-

√

-

-

-

-

-

-

1

Intrahepatic cholangiocarcinoma (ICC)

-

-

-

-

-

-

√

-

-

1

Kidney cancer

√

-

-

-

-

-

√

-

-

2

Lung cancer

-

-

√

-

-

√

-

√

-

3

Lupus nephritis

-

√

-

-

-

√

-

-

-

2

Malignant melanoma

√

-

-

-

√

-

-

-

-

2

Non-alcoholic fatty liver disease (NAFLD)

-

-

-

√

√

-

-

-

-

2

Non-small cell lung cancer (NSCLC)

√

√

√

-

√

-

-

-

-

4

Ovarian cancer (OC)

√

-

√

-

-

√

√

-

-

4

Oral Squamous Cell Carcinoma (OSCC)

-

-

√

-

√

-

-

-

-

2

Pancreatic cancer

-

√

-

√

√

-

√

-

-

4

Papillary thyroid carcinoma (PTC)

√

-

√

-

-

-

-

-

-

2

Pituitary adenoma

√

-

-

√

-

-

-

-

-

2

Polycystic Kidney Disease

√

-

-

-

-

-

-

-

-

1

Polycystic liver disease

√

-

-

-

-

-

-

-

-

1

Prostate cancer

√

-

√

√

-

√

-

√

√

6

Retinoblastoma

-

-

-

-

-

-

-

-

√

1

Schizophrenia

√

√

-

-

√

√

-

-

-

4

Serous ovarian cancer

-

-

√

-

-

-

-

-

-

1

Ulcerative colitis (UC)

-

-

√

-

-

√

-

-

-

2

Total (42)

17

12

13

10

13

16

10

5

3