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Table 4 The assessment of heterogeneity and publication bias

From: Genetic impact of methylenetetrahydrofolate reductase (MTHFR) polymorphism on the susceptibility to colorectal polyps: a meta-analysis

polymorphism Comparison I2 P value Model Begg’s test Egger’s test
z P t P
rs1801133 allele T vs. allele C 0.0% 0.736 Fixed 0.69 0.492 0.46 0.651
TT vs. CC 0.0% 0.799 Fixed 0.90 0.367 0.75 0.463
CT vs. CC 0.0% 0.705 Fixed 0.79 0.428 −0.41 0.685
CT + TT vs. CC 0.0% 0.725 Fixed 0.11 0.916 −0.02 0.984
TT vs. CC + CT 0.0% 0.790 Fixed 0.73 0.463 0.70 0.492
carrier T vs. carrier C 0.0% 0.999 Fixed 0.32 0.751 0.27 0.787
rs1801131 allele C vs. allele A 9.6% 0.354 Fixed 1.16 0.245 1.41 0.195
CC vs. AA 14.3% 0.311 Fixed 1.52 0.128 1.96 0.085
AC vs. AA 0.0% 0.800 Fixed 0.45 0.655 −0.25 0.807
AC + CC vs. AA 0.0% 0.623 Fixed 1.34 0.180 0.64 0.541
CC vs. AA+AC 8.3% 0.366 Fixed 1.52 0.128 2.17 0.061
carrier C vs. carrier A 0.0% 0.918 Fixed 0.98 0.325 1.04 0.327