Skip to main content

Table 4 Minor allele counts for rare nonsynonymous deleterious variants, odds ratios and p-values from Fisher’s exact test for genes of interest

From: Identification of novel sarcoma risk genes using a two-stage genome wide DNA sequencing strategy in cancer cluster families and population case and control cohorts

Gene of interest

Allele Counts (# NS Variants) ISKSa

Allele Counts (# NS Variants) MGRBb

Odds ratio

p-valuec

Q-value d

ABCB5

30 (17)

32 (16)

1.79

0.02

0.16

ARHGAP39

1 (1)

3 (1)

2.07

0.45

1.00

BEAN1

1 (1)

0 (0)

0

1

1.00

C16orf96

4 (4)

12 (9)

1.81

0.296

0.237

KIF2C

0 (0)

1 (1)

0

1

1.00

PDIA2

5 (5)

1 (1)

4.07

0.23

1.00

UVSSA

21 (8)

25 (6)

1.29

0.45

1.00

ZFP69B

2 (2)

16 (4)

0.51

0.55

1.00

  1. aISKS International Sarcoma Kindred Study. bMGRB Medical Genome Reference Bank. cUncorrected p-value. dBonferroni corrected p-value for multiple testing (α = 0.05)