Fig. 5From: MLH1 germline mutation associated with Lynch syndrome in a family followed for more than 45 yearsPCR/direct sequencing analysis of genomic DNA. Sequence of the PCR product showing the breakpoint region within MLH1 intoron 3 and LRRFIP2 intron 16 of the junction fragment. Characterization of the deletion breakpoint, indicated that the MLH1 structural abnormal genes are a MLH1 4-19 deletion, nucleotides: 129,810 - 118,893, size: 89,083 bpBack to article page