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Table 4 Single variant test and cumulative allele odds ratio of RNF213 rare variants

From: Rare RNF213 variants and the risk of intracranial artery stenosis/occlusion disease in Chinese population: a case-control study

Variant

Ref

Alt

Case_Ref

Case_Alt

Control_Ref

Control_Alt

OR

95%CI

p value*

Chr17:78247076–78,247,076

C

–

499

1

2430

0

–

–

0.171

Chr17:78298891

T

C

499

1

2430

0

–

–

0.171

Chr17:78307986

G

T

499

1

2430

0

–

–

0.171

Chr17:78311532

C

T

498

2

2419

11

0.88

(0.20–4.00)

1.000

Chr17:78311620

A

G

499

1

2430

0

–

–

0.171

Chr17:78313764

C

T

494

6

2414

16

1.83

(0.71–4.71)

0.248

Chr17:78318465

C

G

496

4

2403

27

0.72

(0.25–2.06)

0.383

Chr17:78319385

T

G

494

6

2408

22

1.33

(0.54–3.30)

0.716

Chr17:78326772

C

T

499

1

2429

1

4.87

(0.30–77.95)

0.312

Chr17:78350088

T

C

489

11

2392

38

1.42

(0.72–2.79)

0.312

Chr17:78353469

T

C

499

1

2430

0

–

–

0.171

Chr17:78354738

G

A

499

1

2430

0

–

–

0.171

Chr17:78355494

C

G

499

1

2429

1

4.87

(0.30–77.95)

0.312

Chr17:78356830

G

T

499

1

2430

0

–

–

0.171

Chr17:78357541

A

T

499

1

2430

0

–

–

0.171

Chr17:78360656

C

T

499

1

2429

1

4.87

(0.30–77.95)

0.312

Chr17:78362497

C

T

499

1

2430

0

–

–

0.171

Chr17:78363181

C

T

499

1

2430

0

–

–

0.171

Total counts

  

8958

42

43,623

117

1.74

(1.23–2.49)

0.002

  1. *P values were calculated using a two-sided Fisher’s exact test
  2. Ref Reference allele(s), Alt Alternate allele(s)
  3. Case = 250 ICASO patients, Control = 1KG Chinese Han population and GeneSky Database(including 1007 healthy individuals)
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BMC Medical Genetics

ISSN: 1471-2350

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