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Table 3 Results of association analysis in the three populations for rs946261

From: A cis-eQTL allele regulating reduced expression of CHI3L1 is associated with late-onset adult asthma in Japanese cohorts

 

Tsukuba GWAS cohort

Tsukuba replication cohort

Hokkaido replication cohort

Meta-analysis

n

RAF

OR

P value

n

RAF

OR

P value

n

RAF

OR

P value

OR

P value

(C)

(95% CI)

(C)

(95% CI)

(C)

(95% CI)

(95% CI)

Asthmatic patients

237

0.68

1.27

0.036

381

0.64

1.00

0.97

428

0.67

1.23

0.032

1.16

0.013

Nonasthmatic individuals

734

0.63

(1.02–1.59)

 

375

0.64

(0.81–1.23)

 

554

0.62

(1.02–1.48)

 

(1.03–1.31)

 
  1. RAF Risk allele frequency