A cis-eQTL allele regulating reduced expression of CHI3L1 is associated with late-onset adult asthma in Japanese cohorts

Table 1 eQTL SNPs of CHI3L1

SNP	Chr1 position	eQTL	Minor allele	Risk allele	Minor allele frequency		Associations with asthma
SNP	Chr1 position	P value	Minor allele	Risk allele	HapMap JPT	Tsukuba GWAS cohort (Nonasthmatic + asthmatic patients)	P value
rs880633	203,183,673	2.5 × 10⁻⁹	C	T	0.31	0.36	0.30
rs946261	203,188,745	8.3 × 10⁻⁹	T	C	0.27	0.36	0.036
rs946262	203,189,101	9.9 × 10⁻¹³	T	T	0.052	0.048	0.94
rs10920579	203,189,844	2.6 × 10⁻¹³	A	A	0.052	0.048	0.94
rs7541061	203,194,239	6.3 × 10⁻¹³	A	A	0.052	0.048	0.94
rs946263	203,196,253	2.5 × 10⁻¹¹	G	A	0.023	0.011	0.85

ISSN: 1471-2350