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Table 1 Correlation between DNA methylation (Probe ID) and gene expression (Gene) in hypoxia

From: HIF-1 transcription activity: HIF1A driven response in normoxia and in hypoxia

ProbeID Gene Δβ HIF1A Log2 FC HIF1A Gene feature CpG feature
 cg01915791 HSPB6 − 0.24969157 0.773186 Body island
 cg02836965 SGCZ −0.21032015 1.47509 Body open sea
 cg03387092 MYLK −0.22225645 0.588606 Body open sea
 cg03905369 EPB41L5 −0.22872718 1.00335 Body open sea
 cg04056576 PPM1L −0.22056766 0.857675 Body shore
 cg04194674 SRCIN1 0.21094717 −0.865002 Body island
 cg06221087 PBX1 −0.20339421 0.535856 Body open sea
 cg08843859 C1orf21 −0.23049642 0.924679 Body open sea
 cg11849717 EGFR − 0.22631862 0.694851 Body island
 cg12743970 PRKCA 0.22709241 −0.728741 Body open sea
 cg14862207 SRCIN1 0.20762646 −0.865002 Body island
 cg16198315 DACH1 0.21650226 −0.533886 Body shore
 cg18277497 FIGN −0.27273159 0.851071 Body open sea
 cg20897616 GABRB3 −0.24454897 1.42689 Body island
 cg21516044 CPE −0.21441006 0.836739 Body shelf
 cg22340526 DPP6 −0.22509589 0.559082 Body shore
 cg24597512 GABRB3 −0.21252389 1.42689 Body shore
 cg24673955 KIF26B −0.20727528 0.682105 Body shore
 cg25005674 PPP2R2B −0.24873958 0.895844 Body open sea
 cg26672287 LTBP1 −0.22576329 0.82036 Body open sea
 cg27262041 NAV2 −0.21068975 0.518347 Body open sea
 cg27637738 EGFR −0.2302424 0.694851 Body open sea
 cg21812277 PARP4 −0.21286384 0.619207 5’UTR shore
 cg08991927 PPP2R2B −0.21036441 0.895844 5’UTR shore
 cg03690837 ETS2 −0.20969341 0.534019 TSS1500 island
 cg11426075 ERRFI1 −0.21603014 0.555979 TSS1500 shore
 cg13495205 AJAP1 −0.21926813 0.818246 TSS1500 island
 cg18115428 SLC35F3 −0.2429891 1.76376 TSS1500 shore
 cg24533917 CHIT1 −0.20768064 2.62046 TSS1500 open sea
 cg26515460 RSPO4 0.21822875 −1.12443 TSS1500 shore
 cg09565404 FER −0.23534751 0.579076 TSS200 shore
 cg13072057 B3GALNT1 −0.21923622 0.54531 TSS200 island
 cg14135988 RAB27B −0.20442834 0.713729 TSS200 island
 cg14744537 RAB27B −0.20487652 0.713729 TSS200 island
ProbeID Gene Δβ Hypoxia Log2 FC Hypoxia Gene feature CpG feature
 cg05502283 NFIX 0.22139292 −0.340491 3’UTR shelf
 cg18834544 PCCA 0.20607751 −0.553331 3’UTR shore
 cg12793733 ATP10D 0.2327763 −0.825063 5’UTR open sea
 cg15524063 ELOVL1 −0.21138562 0.340798 5’UTR island
 cg15883603 SORBS2 0.28146882 −1.01339 5’UTR open sea
 cg20164964 TSPAN9 0.21253777 −0.411039 5’UTR open sea
 cg22871175 FAM19A4 0.20371924 −0.80565 5’UTR open sea
 cg05490591 MSI2 0.21667094 −0.7364 Body open sea
 cg07238439 TPCN1 0.21883677 −0.778461 Body open sea
 cg11197258 NCOR2 0.2523067 −0.583474 Body open sea
 cg13764850 ROR2 0.21935471 −0.372244 Body shelf
 cg14377416 VAV2 0.21872117 −0.347793 Body open sea
 cg15570035 ANKRD17 0.20105082 −0.459873 Body open sea
 cg22218512 ACVRL1 0.20924927 −0.735922 Body shore
 cg26803268 CACNB2 0.2033665 −0.661703 Body open sea
 cg27262041 NAV2 0.21727999 −0.666122 Body open sea
 cg06888900 BCAR1 0.20187808 −0.642616 TSS1500 shore
 cg07815799 ARHGEF4 0.27465952 −0.577694 TSS200 island
  1. Δβ Hypoxia: Delta beta in shCTR HYP vs shCTR NX.; Δβ HIF1A: Delta beta in shHIF1A HYP vs shCTR HYP; Log2 FC: log2 of expression fold change