Fig. 2
From: HIF-1 transcription activity: HIF1A driven response in normoxia and in hypoxia
Genes regulated upon hypoxia exposure, in presence and absence of HIF1A. a The differentially expressed genes in shHIF1A HYP vs shCTR HYP and shCTR HYP vs shCTR NX were crossed and 674 genes were found commonly regulated. Of note, 420 out of 674 genes show the same trend of regulation and are named Hypoxia targets; 254 out of 674 genes show an opposite regulation and are named HIF1A targets. b The fold change of Hypoxia targets expression (Log2) in both gene lists is shown in the graph; KEGG pathways analysis (pvalue ≤ 0.05) is reported and the negative Log2 pvalue is shown on X-axis. c The fold change of HIF1A direct targets expression (Log2) in both gene lists is shown in the graph; KEGG pathways analysis (pvalue ≤ 0.05) is reported and the negative Log2 pvalue is shown on X-axis