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Fig. 3 | BMC Medical Genetics

Fig. 3

From: The association between interleukin-6 gene -174G/C single nucleotide polymorphism and sepsis: an updated meta-analysis with trial sequential analysis

Fig. 3

TSA of the analysis on the association between IL-6-174 G/C polymorphism and the risk of sepsis in non-adults under dominant model. A type I error of 5%, power of 80%, relative risk reduction of 20% were defined and control event proportion was an average of each included study. The vertical red line represents the required information size (sample size). The red curves represent the O’Brien-Fleming boundary and futility boundary. The blue line represents the cumulative Z-curve. RIS, required information size

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BMC Medical Genetics

ISSN: 1471-2350

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