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Table 2 Two-generation analysis of mutation genes and NK cell function

From: Novel mutations of STXBP2 and LYST associated with adult haemophagocytic lymphohistiocytosis with Epstein-Barr virus infection: a case report

  Patient Mother Father
Mutation genes STXBP2 + +
LYST + +
LRBA + +
AIRE + +
IRF8 + +
NK cell function Killing activity (normally ≥15.11%) 6.50% 4.97% 16.18%
Activated CD107a level (normally ≥40%) 33.24% 22.60% 51.20%
Resting CD107a level (normally ≥5%) 14.90% 3.14% 15.87%
  1. +, mutant; −, wild type