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Table 2 Associations of rs10519225 and rs10519255 with COPD

From: A functional variant alters binding of activating protein 1 regulating expression of FGF7 gene associated with chronic obstructive pulmonary disease

Genotype

Frequency

  

Controls

COPD cases

OR (95% CI)

P value

rs12905203 A/G

 AA

205

138

1.516 (1.127–2.038)

0.005

 AG

96

110

 GG

10

10

 MAF

0.1865

0.2519

rs10519225 G/A

 GG

211

148

1.427 (1.048–1.943)

0.024

 GA

92

104

 AA

8

6

 MAF

0.1736

0.2248

rs4480740 G/A

 GG

222

168

1.237 (0.8958–1.708)

0.196

 GA

82

86

 AA

7

4

 MAF

0.1822

0.1543

  1. Statistically significance was calculated using logistic regression with an additive model for both variants