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Table 1 Characteristics of the analyzed groups

From: The role of MMP-12 gene polymorphism − 82 A-to-G (rs2276109) in immunopathology of COPD in polish patients: a case control study

Groups (N)

Age

Sex

FEV1

FEV1/FVC

Smokers

(years)

(women/men)

(% predicted)

(% predicted)

(%)

COPD (335)

67.9 ± 9.2

248/87b

55.5 ± 18.5b

52.2 ± 16.0b

100b

CTR (309)

68.0 ± 6.6

80/229

91.7 ± 22.8

89.2 ± 25.8

35.5

CTR smokers (110)

68.4 ± 5.2

73/37

93.3 ± 22.0

91.1 ± 19.5

100

CTR non-smokers (199)

65.8 ± 9.6

157/42

91.0 ± 23.6

88.1 ± 28.7

0

COPDa (60)

70.4 ± 9.0

13/47b

46.6 ± 18.5b

58.1 ± 16.4b

100b

CTRa (61)

67.8 ± 6.7

46/15

90.4 ± 22.5

92.6 ± 23.2

37.7

CTR smokersa (23)

67.7 ± 5.6

15/8

93.2 ± 21.9

88.2 ± 16.4

100

CTR non-smokersa (38)

67.9 ± 7.6

31/7

90.6 ± 22.0

90.7 ± 18.0

0

  1. N numbers of individuals, COPD chronic obstructive pulmonary disease groups, CTR control group; a, groups for protein levels analyses, FEV1 forced expiratory volume in 1 s, FEV1/FVC Tiffeneau-Pinelli index – ratio of forced expiratory volume in 1 s and forced vital capacity; b, difference to the control group statistically significant at the level of p < 0.00001