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Table 3 Subgroup analysis of the GSTP1 rs1695 A/G polymorphism by race, genotyping assay and control source

From: Glutathione S-transferase pi 1 variant and squamous cell carcinoma susceptibility: a meta-analysis of 52 case-control studies

Factor Subgroup Index Allele Carrier Homozygote Heterozygote Dominant Recessive
Race Asian OR (95% CIs) 1.00 (0.89~1.12) 0.98 (0.86~1.11) 1.29 (0.94~1.76) 0.90 (0.78~1.04) 0.94 (0.82~1.08) 1.35 (0.99~1.83)
   P a 0.948 0.716 0.114 0.139 0.361 0.058
   Case/control 1696/2139 1696/2139 1696/2139 1696/2139 1696/2139 1696/2139
   Study number 10 10 10 10 10 10
Race Caucasian OR (95% CIs) 0.98 (0.93~1.03) 0.98 (0.82~1.04) 1.00 (0.89~1.12) 0.94 (0.87~1.01) 0.95 (0.89~1.02) 1.02 (0.91~1.14)
   P a 0.358 0.447 0.984 0.099 0.153 0.716
   Case/control 5968/9719 5968/9719 5968/9719 5968/9719 5968/9719 5968/9719
   Study number 30 30 30 30 30 30
genotyping assay PCR-RFLP OR (95% CIs) 0.99 (0.94~1.03) 0.99 (0.93~1.04) 1.01 (0.91~1.12) 0.96 (0.90~1.03) 0.97 (0.91~1.03) 1.01 (0.91~1.12)
   P a 0.542 0.579 0.874 0.260 0.351 0.824
   Case/control 8008/11,342 8008/11,342 8008/11,342 8008/11,342 8008/11,342 8008/11,342
   Study number 42 42 42 42 42 42
control source PB OR (95% CIs) 0.98 (0.94~1.03) 0.98 (0.93~1.04) 1.00 (0.90~1.12) 0.96 (0.89~1.03) 0.96 (0.90~1.03) 1.02 (0.92~1.13)
   P a 0.519 0.572 0.943 0.214 0.287 0.751
   Case/control 6697/10,170 6697/10,170 6697/10,170 6697/10,170 6697/10,170 6697/10,170
   Study number 31 31 31 31 31 31
control source HB OR (95% CIs) 0.98 (0.91~1.06) 0.98 (0.90~1.07) 1.00 (0.84~1.20) 0.95 (0.86~1.06) 0.96 (0.87~1.07) 1.01 (0.85~1.19)
   P a 0.586 0.638 0.977 0.377 0.461 0.944
   Case/control 2771/3946 2771/3946 2771/3946 2771/3946 2771/3946 2771/3946
   Study number 19 19 19 19 19 19
  1. Pa, P value of association test
  2. PCR-RFLP polymerase chain reaction-restriction fragment length polymorphism, PB population-based, HB hospital-based, OR odds ratio, CIs confidence intervals