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Table 1 Characteristics of the studies included in the meta-analysis for rs2195239

From: Association between the insulin-like growth factor 1 gene rs2195239 and rs2162679 polymorphisms and cancer risk: a meta-analysis

First author

Year

Country/Region

Ethnicity

Cancer type

Genotyping method

Age(y)

Case/Control

Control source

Case

Control

HWE

GG

GC

CC

GG

GC

CC

Chia [15]

2008

USA

Mix

TGCT

Taqman

≤45/≤45

PB

332

209

32

395

252

50

Y

Patel [17]

2008

USA/Europe

Mix

Breast cancer

Taqman

NR

PB

434

2440

3699

532

3121

4819

Y

Birmann [18]

2009

USA

Caucasian

Multiple myeloma

Taqman

30–75/30–75

PB

9

26

43

11

63

85

Y

Dong [19]

2011

USA

Mix

Pancreatic cancer

MassArray and TaqMan

14–80/14–80

HB

385

270

40

409

260

35

Y

Ennishi [20]

2011

Japan

Asian

Stomach cancer

Taqman

NR

HB

230

346

127

447

703

312

Y

Nakao [21]

2011

Japan

Asian

Pancreatic cancer

Taqman

20–79/20–79

HB

54

95

27

431

673

298

Y

Qian [22]

2011

China

Asian

Breast cancer

Taqman

NR

HB

147

181

75

135

193

75

Y

Shi [23]

2016

Canada

Mix

Breast cancer

Illumina GoldenGate

40–80/40–80

PB

349

267

25

453

301

52

Y

  1. Abbreviations: TGCT testicular germ cell tumors, PB population-based, HB hospital-based, HWE Hardy-Weinberg equilibrium, Y polymorphisms conformed to HWE in the control group, N polymorphisms did not conform to HWE in the control group, NR not reported