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Fig. 4 | BMC Medical Genetics

Fig. 4

From: Modeling gene-environment interactions in longitudinal family studies: a comparison of methods and their application to the association between the IGF pathway and childhood obesity

Fig. 4

Estimated type I error rates for the compared analytical approaches. Type I error rates were estimated for each analytical approach as the proportion of false positive results (p-value < 0.05) calculated over 2000 simulation replicates with no interaction effect. Estimated type I error rates are shown for gene-environment (GE) interaction effect (left panel; simulation model includes a genetic main effect) and gene-time-environment (GTE) interaction effect (right panel; simulation model includes a gene-time interaction effect). The environmental main effect (βE) was included for all null scenarios

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BMC Medical Genetics

ISSN: 1471-2350

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