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Table 6 Estimated frequencies of haplotypes consisting of EREG SNPs in EPTB and controls

From: Polymorphism in the EREG gene confers susceptibility to tuberculosis

Haplotype

EPTB (%)a

Control (%)a

χ2

P

OR[95%CI]

CACAT

145.99 (36.5)

303.06 (25.3)

16.35

0.000053

1.65 (1.29-2.10)

CGATT

45.99 (11.5)

104.24 (8.7)

2.29

0.13

1.33 (0.92-1.92)

CGCTT

149.01 (37.3)

607.71 (50.6)

26.09

3.32×10 -7

0.55 (0.43-0.69)

TGCAG

47.00 (11.7)

101.12 (8.4)

3.35

0.070

1.41 (0.98-2.03)

  1. a Frequencies <0.03 were excluded from the analysis
  2. Global p<0.01
  3. The order of the SNPs in the haplotype is rs10518126 rs2367707 rs3806794 rs6446993 rs6836436
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BMC Medical Genetics

ISSN: 1471-2350

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