Fig. 2
From: Integrated molecular characterization of adult soft tissue sarcoma for therapeutic targets
Mutation signature and microsatellite instability (MSI) clustering. a Contribution of the different types of substitutions in all patients. b The dendrogram was determined using the frequency of substitutions motif by hierarchical clustering. Red lines indicate clusters of hypermutators. Consensus plot for three non-negative matrix factorization (NMF) clusters (10 runs) by mRNA expression across the 42 MSI signature genes. Red color indicates hypermutators