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Table 2 SNP characteristics and multivariate logistics regression analysis

From: Genetic associations in community context: a mixed model approach identifies a functional variant in the RBP4 gene associated with HDL-C dyslipidemia

Gene Symbol SNP Alleles Risk Allele Risk Allele Frequency Odds Ratio (95% Confidence Interval) P-value
Normal HDL-C Abnormal HDL-C
ADFP rs35629534 A/G A 0.95 0.96 1.22 (0.74–2.13) 0.464
ADFP rs3824369 C/T C 0.49 0.51 1.10 (0.89–1.37) 0.369
ADIPOQ rs1063537 C/T C 0.90 0.92 1.23 (0.88–1.76) 0.245
ADIPOQ rs182052 A/G A 0.33 0.36 1.11 (0.90–1.37) 0.325
ADIPOQ rs6773957 A/G A 0.38 0.37 0.99 (0.81–1.22) 0.941
ATGL rs1138714 A/G A 0.45 0.47 1.14 (0.92–1.40) 0.223
CART rs3763154 T/C T 0.57 0.58 1.06 (0.87–1.30) 0.555
CART rs2320167 A/G A 0.10 0.11 1.17 (0.84–1.60) 0.344
GHRL rs35684 A/G A 0.73 0.76 1.22 (0.97–1.55) 0.089
GHRL rs2075356 C/T C 0.11 0.11 1.02 (0.74–1.39) 0.910
GHRL rs26311 C/G C 0.88 0.86 0.87 (0.65–1.17) 0.344
GHRL rs4684677 A/T A 0.06 0.07 1.01 (0.66–1.51) 0.971
GHRL rs26802 G/T G 0.30 0.28 0.91 (0.73–1.14) 0.409
MCHR1 rs882111 G/T G 0.93 0.92 0.93 (0.64–1.37) 0.698
MCHR1 rs9611386 A/G A 0.95 0.95 0.95 (0.62–1.52) 0.837
MCHR rs133074 C/T C 0.50 0.51 1.07 (0.88–1.31) 0.488
MCHR rs133073 C/T C 0.42 0.41 0.91 (0.74–1.11) 0.354
PLIN rs4932241 A/C A 0.31 0.30 0.91 (0.72–1.16) 0.459
PLIN rs894160 C/T C 0.74 0.72 0.85 (0.67–1.09) 0.190
PLIN rs2289487 C/T C 0.31 0.33 1.15 (0.91–1.45) 0.253
RBP4 rs3758539 C/T C 0.83 0.87 1.45 (1.08–1.96) 0.015*
RBP4 rs779604024 A/G A 0.91 0.91 1.12 (0.79–1.62) 0.544
RBP4 rs10882280 A/G A 0.09 0.09 0.94 (0.65–1.33) 0.720
TTS2.2 rs4131364 A/G A 0.50 0.48 0.90 (0.73–1.11) 0.308
NAMPT rs7789066 A/G A 0.94 0.93 0.92 (0.61–1.41) 0.689
NAMPT rs6947766 C/T C 0.74 0.76 1.12 (0.89–1.42) 0.326
NAMPT rs6963243 C/G C 0.24 0.27 1.22 (0.97–1.54) 0.093
NAMPT rs3801266 C/T C 0.19 0.17 0.87 (0.66–1.14) 0.332
NAMPT rs10808150 A/G A 0.43 0.43 1.05 (0.85–1.29) 0.648
NAMPT rs2098291 C/T C 0.69 0.68 0.96 (0.77–1.19) 0.684
PLA2G16 rs7101608 G/C G 0.45 0.49 1.14 (0.94–1.39) 0.194
  1. *P-value< 0.05; All analyses were adjusted for age, sex, BMI, smoking, and comorbidities (diabetes and hypertension)