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Table 6 Phenotypic and genetic correlations between measures of body composition at birth and in adulthood

From: Genetic insights into fetal growth and measures of glycaemic regulation and adiposity in adulthood: a family-based study

 

Birth weight (g)

Ponderal index

Traits measured in adulthood

n

ρP

ρG (95% CI)

n

ρP

ρG (95% CI)

Weight (kg)

411

0.25*

0.38 (0.09; 0.67)*#

411

0.15

0.12 (- 0.31; 0.55)

Height (cm)

411

0.16*

0.17 (- 0.14; 0.48)

411

- 0.08

0.33 (- 0.02; 0.68)

Waist (cm)

406

0.08

0.08 (- 0.27; 0.43)

406

0.08

- 0.24 (- 0.65; 0.17)

Waist-hip ratio

406

- 0.03

0.03 (- 0.32; 0.38)

406

- 0.01

- 0.36 (- 0.75; 0.03)

BMI (kg/m2)

411

0.16*

0.24 (- 0.07; 0.55)

411

0.12

- 0.01 (- 0.42; 0.40)

Fat mass (kg)

376

0.04

0.04 (- 0.29; 0.37)

376

0.01

- 0.06 (- 0.47; 0.35)

  1. Phenotypic correlations between traits were estimated as ρP (95% CI), and genetic correlations were estimated as ρG (95% CI). All correlations were adjusted for sex. *Correlation significantly different from zero (p < 0.05). #Correlation remained significant following adjustment for both birth weight and adult BMI susceptibility SNPs. All genetic correlations were significantly different from 1 (p < 0.05)