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Table 4 Correlations between measures of birth body composition and adult measures of insulin sensitivity

From: Genetic insights into fetal growth and measures of glycaemic regulation and adiposity in adulthood: a family-based study

  Birth weight (g) Ponderal index
  n ρP ρG (95% CI) n ρP ρG (95% CI)
Insulin sensitivity in adulthood
HOMA-IR 376 - 0.12 - 0.31 (- 0.64; 0.02) 376 - 0.09 - 0.35 (- 0,76; 0.06)
Matsuda insulin sensitivity index 376 0.15* 0.36 (0.03; 0.69)*# 376 0.14* 0.52 (0.15; 0.89)*#
  1. Phenotypic correlations between traits were estimated as ρP, and genetic correlations were estimated as ρG (95% CI). Correlations were estimated in non-diabetic relatives of patients with type 2 diabetes mellitus. All correlations were adjusted for sex. *Correlation significantly different from zero (p < 0.05). #Correlation remained significant following adjustment for both birth weight and adult type 2 diabetes susceptibility SNPs. All genetic correlations were significantly different from 1 (p < 0.05)