Body composition measured at birth | ||||
Trait | n | h2 (95% CI) | c2 (95% CI) | e2 (95% CI) |
Birth weight (g) | 297 | 0.80 (0.37; 1.23)* | 0.05 (−0.20; 0.30) | 0.15 (−0.09; 0.39) |
Ponderal index | 296 | 0.46 (0.01; 0.91)* | 0.02 (− 0.18; 0.22) | 0.53 (0.22; 0.84)* |
Birth length (cm) | 296 | 0.15 (−0.54; 0.84) | 0.17 (−0.18; 0.52) | 0.67 (0.30; 1.04)* |
Adult body composition | ||||
Weight (kg) | 406 | 0.35 (0.04; 0.66)* | 0.01 (−0.15; 0.17) | 0.64 (0.42; 0.86)* |
Height (cm) | 406 | 0.30 (0.01; 0.59)* | 0.32 (0.12; 0.52)* | 0.39 (0.21; 0.57)* |
Waist (cm) | 398 | 0.28 (−0.01; 0.57)* | 0.03 (−0.13; 0.19) | 0.69 (0.49; 0.89)* |
Waist-hip ratio | 397 | 0.34 (0.14; 0.54)* | 0 (0) | 0.66 (0.46; 0.86)* |
BMI (kg/m2) | 406 | 0.32 (0.03; 0.61)* | 0.07 (−0.07; 0.21) | 0.61 (0.39; 0.83)* |
Fat mass (kg) | 338 | 0.50 (0.26; 0.74)* | 0 (0) | 0.50 (0.26; 0.74)* |
Fat free mass (kg) | 338 | 0.09 (−0.52; 0.70) | 0.17 (−0.16; 0.50) | 0.74 (0.39; 1.09)* |
Adult measures of glycaemic control | ||||
Insulin secretion | ||||
HOMA-B (%) | 367 | 0.27 (−0.06; 0.60)* | 0.02 (−0.16; 0.20) | 0.71 (0.38; 1.04)* |
BIGTT-AIR | 312 | 0.31 (0.09; 0.53)* | 0 (0) | 0.69 (0.47; 0.91)* |
Insulinogenic index | 318 | 0.25 (0.03; 0.47)* | 0 (0) | 0.75 (0.53; 0.97)* |
AUC insulin 4 h (pmol/l*min) | 302 | 0.25 (1.01; 0.49)* | 0 (0) | 0.75 (0.51; 0.99)* |
Insulin sensitivity | ||||
HOMA-IR | 367 | 0.37 (0.12; 0.62)* | 0 (0) | 0.63 (0.38; 0.88)* |
Matsuda insulin sensitivity index | 367 | 0.31 (0.07; 0.55)* | 0 (0) | 0.69 (0.45; 0.93)* |