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Table 4 Allelic distribution of patient population after stratifying to moderate-obese and extreme-obese groups based on their BMI

From: Association of Uncoupling Protein 1 (UCP1) gene polymorphism with obesity: a case-control study

Gene

SNP

Allele

Control

Moderate obese

Model 1a

Model 2b

Extreme obese

Model 1a

Model 2b

OR

98.75%CI

P value

OR

98.75%CI

p value

OR

98.75%CI

P value

OR

98.75%CI

p value

UCP1

rs1800592

A

227

271

Ref

     

172

Ref

     

G

83

143

1.44

1.96–2.18

0.026

1.52

0.95–2.46

0.027

88

1.39

0.88–2.21

0.067

1.39

0.88–2.23

0.072

rs10011540

T

283

382

Ref

     

245

Ref

     

G

27

32

0.87

0.44–1.73

0.633

1.01

0.46–2.23

0.967

15

0.64

0.28–1.48

0.183

0.58

0.25–1.37

0.113

rs3811791

T

298

378

Ref

     

246

Ref

     

C

12

36

2.36

1.0–5.56

0.011

2.89

1.08–7.73

0.007

14

1.41

0.52–3.86

0.390

1.32

0.47–3.71

0.494

NPC1

rs1805081

T

275

371

Ref

     

234

Ref

     

C

35

43

0.91

0.50–1.66

0.698

0.78

0.39–1.56

0.376

26

0.87

0.44–1.73

0.619

0.86

0.43–1.75

0.612

rs1805082

T

225

306

Ref

     

185

Ref

     

C

85

108

0.93

0.61–1.42

0.688

0.91

0.56–1.49

0.637

75

1.07

0.67–1.71

0.705

1.04

0.65–1.68

0.813

  1. Data with significant p-value (< 0.0125) are shown in bold
  2. aUnadjusted and bAdjusted for Age, Gender and T2DM