Table 2 Clinical characteristics of the South Indian nephrotic syndrome cohort
Characteristics | Total (n = 25) (%) | |
|---|---|---|
Sex | Male | 18 (72) |
Female | 7 (28) | |
Age at diagnosis | Median (years) | 2.5 years |
Infantile (4–12 months) | 3 (12) | |
Early childhood (13 months −5 years) | 16 (64) | |
Late childhood (6–12 years) | 4 (16) | |
Adolescent (13–18 years) | 2 (8) | |
Family history | Yes | 7 (28) |
No | 18 (72) | |
Parental consanguinity | Yes | 5 (20) |
No | 20 (80) | |
Steroid resistance | primary steroid resistance | 24 (96) |
Secondary steroid resistance | 1 (4) | |
Histopathology subtype | Focal segmental glomerulosclerosis (FSGS) | 14 (56) |
Minimal change disease (MCD) | 3 (12) | |
Mesangial hypercellularity (MHC) | 6(24) | |
Diffuse mesangial sclerosis (DMS) | 1 (4) | |
Unknown | 1 (4) | |
Renal outcome | Remission | 2 (8) |
Persistent relapse | 9 (36) | |
Chronic Kidney disease Stage II-IV | 4 (16) | |
End stage renal disease | 5 (20) | |
Underwent renal transplant | 1 (4) | |
Dead | 4 (16) | |