Table 1 Clinical characteristics of probands with homozygous LEPR mutations
From: Identification of novel LEPR mutations in Pakistani families with morbid childhood obesity
|  | Proband OB4–7 | Proband OB25–4 |
|---|---|---|
Family ID | OB4 | OB25 |
Sex | Female | Female |
Age at enrolment (years) | 12.18 | 1.03 |
Age at obesity onset | 40Â days | 60Â days |
Height (cm) | 152.0 | 76.2 |
Weight (kg) | 145.0 | 18.0 |
BMI (kg/m2) | 62.8 | 31.0 |
BMI SDS | 4.49 | 6.49 |
Waist circumference (cm) | 137.0 | 73.6 |
Family history of obesity | No | No |
Related co-morbidities | Diabetes | Diabetes, dyslipidaemia, hepatic and renal function disorder |
Mutation type | Frameshift | Missense |