Table 4 Stratification analysis for the rs2854744 genotype distribution and acromegaly risk by gender
From: Association between acromegaly and a single nucleotide polymorphism (rs2854744) in the IGFBP3 gene
Genotypea | Case [N(%)] | Control [N(%)] | OR (95% CI) | P value |
|---|---|---|---|---|
n = 102 | n = 143 | |||
Female | ||||
AA | 29(64.4) | 29(39.7) | 0.011 | |
AC | 15(33.3) | 33(45.2) | ||
CC | 1(2.2) | 11(15.1) | ||
Additive | 0.385(0.206–0.72) | 0.002 | ||
Dominant | 0.364(0.168–0.785) | 0.009 | ||
Recessive | 0.128(0.016–1.029) | 0.054 | ||
Male | ||||
AA | 34 (61.8) | 43(62.3) | 0.917 | |
AC | 18(32.7) | 21(30.4) | ||
CC | 3(5.5) | 5(7.2) | ||
Additive | 0.963(0.527–1.762) | 0.903 | ||
Dominant | 1.021(0.492–2.12) | 0.954 | ||
Recessive | 0.738(0.169–3.236) | 0.972 | ||