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Table 2 IGFBP3 rs2854744 genotype distribution in acromegaly patients and controls

From: Association between acromegaly and a single nucleotide polymorphism (rs2854744) in the IGFBP3 gene

Genotype

Case [N(%)]a

Control [N(%)]b

MAF

PHWE

OR (95% CI)

P

AA

63(63)

72(50.7)

0.262

0.236

1

 

AC

33(33)

54(38)

  

0.698(0.403–1.21)

0.2

CC

4(4)

16(11.3)

  

0.286(0.091–0.899)

0.032

A allele

159(79.5)

198(69.7)

  

1

 

C allele

41(20.5)

86(30.3)

  

0.594(0.388–0.909)

0.016

  1. aGenotypic data for 100 subjects in the case group were available. bGenotypic data for 142 subjects in the control group were available. MAF minor allele frequency, HWE Hardy-Weinberg equilibrium. Significant associations are marked in bold