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Fig. 3 | BMC Medical Genetics

Fig. 3

From: Potential role for nectin-4 in the pathogenesis of pre-eclampsia: a molecular genetic study

Fig. 3

Nectin-4 immunostaining of placental tissue sections. Polyclonal rabbit antibodies raised against the cytoplasmic domain of the human nectin-4 (a, b, d and e) or polyclonal goat antibodies raised against the C-terminal domain of the human nectin-4 (c and f) were used. Positive staining was apparent in the cytoplasm and cell membrane at the apical side of the syncytiotrophoblasts (arrows). Cytotrophoblasts were also positive (arrowheads, insets). The nectin-4 signals were much stronger in pre-eclampsia (d, e and f) compared with uncomplicated normotensive pregnancy (a, b, and c). Original magnifications a-f: 400 x. Scale bars, 100 μm

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