Skip to main content

Table 4 Stratified analysis of SNPs in a recessive model

From: Notch polymorphisms associated with sensitivity of noise induced hearing loss among Chinese textile factory workers

SNPs

Group

Genotype

Duration of noise exposed work (years)

Expose level with noise (dB)

≤ 16

>  16

≤ 85

85–92

>  92

rs3124594

case

GG

217

261

212

96

170

AG/AA

20

37

31

9

17

control

GG

183

231

189

73

152

AG/AA

67

54

43

22

56

P a

 

< 0.001

0.03

0.083

0.004

0.001

Adjusted OR

 

4.20

1.67

1.55

3.29

3.65

(95% CI)b

 

(2.44–7.24)

(1.06–2.63)

(0.94–2.57)

(1.40–7.71)

(2.03–6.57)

rs3124599

case

AA

98

125

97

40

86

AG/GG

139

173

146

65

101

control

AA

102

100

98

32

72

AG/GG

148

185

134

63

136

P a

 

0.902

0.089

0.607

0.516

0.021

Adjusted OR

 

1.05

1.36

0.91

1.29

1.59

(95% CI)b

 

(0.73–1.51)

(0.97–1.90)

(0.63–1.32)

(0.71–2.33)

(1.06–2.39)

rs3124603

case

CT/TT

68

72

70

27

43

CC

169

226

173

78

144

control

CT/TT

47

58

38

21

46

CC

203

227

194

74

162

P a

 

0.010

0.269

0.001

0.551

0.835

Adjusted OR

 

1.73

1.24

2.06

1.19

1.08

(95% CI)b

 

(1.13–2.66)

(0.84–1.84)

(1.32–3.22)

(0.61–2.31)

(0.67–1.75)

  1. aTwo-sided χ2 test
  2. bAdjusted for age, sex, alcohol and tobacco use in a logistic regression model