Mutational screening of inverted formin 2 in adult-onset focal segmental glomerulosclerosis or minimal change patients from the Czech Republic

Table 1 Clinical data of 109 patients with FSGS/MCD included in the analysis of INF2

Characteristic	Group	Number/Value
Diagnosis	FSGS	77 (70.6%)
Diagnosis	MCD	32 (29.4%)
Sex	Male	51 (46.8%)
Sex	Female	58 (53.2%)
Family history	Positive	19 (17.4%)
Family history	Negative	90 (82.6%)
NS at the time of diagnosis	Yes	78 (71.6%)
NS at the time of diagnosis	No	31 (28.4%)
Effect of corticosteroid therapy	Sensitive	34 (31.2%)
	Resistant	41 (37.6%)
	No therapy	34 (31.2%)
Mean age at the time of diagnosis	Years	41.44 ± 18.91
Mean proteinuria at the time of diagnosis	All: Grams/24 h	5.67 ± 4.64
	FSGS: Grams/24 h	4.99 ± 4.14
	MCD: Grams/24 h	7.42 ± 5.32
Mean serum albumin level at the time of diagnosis	All: Grams/Litre	28.05 ± 9.48
	FSGS: Grams/Litre	30.36 ± 9.1
	MCD: Grams/Litre	22.15 ± 7.67
Average serum creatinine level at the time of diagnosis	All: μmol/Litre	109.52 ± 61.26
	FSGS: μmol/Litre	112.05 ± 52.21
	MCD: μmol/Litre	103.31 ± 78.91

Data are presented by mean ± SD or number (percentage)
FSGS Focal segmental glomerulosclerosis, MCD Minimal change disease, NS Nephrotic syndrome (defined as presence of proteinuria ≥3 g/24 h plus serum albumin level ≤ 30 g/L)

ISSN: 1471-2350