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Table 6 Haplotype analysis for the correlation between CTLA-4 and GD susceptibility

From: Correlation between CTLA-4 and CD40 gene polymorphisms and their interaction in graves’ disease in a Chinese Han population

 

Haplotype

GD %

Control %

Fisher’s P

Person’s P

OR (95% CI)

H1

CCGCCAC

5.6

4.4

0.725096

0.725093

1.109 (0.624–1.969)

H2

CCGCCGC

2.0

6.0

0.000125

0.000124

0.263 (0.127–0.544)

H3

CCACCAC

7.5

1.7

0.000102

0.000101

4.056 (1.903–8.646)

H4

TCGCTGC

58.6

36.2

< 0.0001

< 0.0001

2.565 (1.883–3.495)

H5

TCACTAC

1.2

9.7

< 0.0001

< 0.0001

0.096 (0.042–0.222)

H6

TCACTGC

3.6

9.7

< 0.0001

< 0.0001

0.289 (0.166–0.503)