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Table 1 Participants’ Demographic, Anthropometric, Biochemical, and Hormonal Characteristics

From: Preliminary study showing no association between G238A (rs361525) tumor necrosis factor-α (TNF-α) gene polymorphism and its serum level, hormonal and biochemical aspects of polycystic ovary syndrome

Characteristic

PCOS patients (n = 111)

Control (n = 105)

p-value

Age (yr)

26.49 ± 6.34

27.46 ± 7.06

0.353

Height (cm)

160.59 ± 5.75

161.31 ± 5.09

0.36

Body weight (kg)

66.74 ± 14.25

62.60 ± 11.70

0.024*

BMI (kg/m2)

25.88 ± 5.24

24.07 ± 4.5

0.008*

WC (cm)

86.57 ± 12.78

82.14 ± 10.66

0.009*

HC (cm)

102.49 ± 12.53

100.99 ± 10.56

0.37

WHR

0.84 ± 0.1

0.81 ± 0.07

0.007*

SBP (mmHg)

105.90 ± 10.62

106.01 ± 17.38

0.55

TC (mg/dl)

187.89 ± 37.03

178.83 ± 32.79

0.05*

TG (mg/dl)

122.45 ± 24.177

105.25 ± 27.33

< 0.0001*

HDL.c (mg/dl)

41.79 ± 11.61

40.3 ± 9.96

0.377

LDL.c (mg/dl)

119.88 ± 26.86

113.67 ± 23.76

0.069

Insulin (μg/dl)

15.64 ± 5.9

8.99 ± 4.36

< 0.0001*

FBS (mg/dl)

68.83 ± 12.35

71.9 ± 14.41

0.089

HOMA-IR

2.59 ± 1.4

1.18 ± 0.99

< 0.0001*

E2 (pg/ml)

57.08 ± 38.96

73.44 ± 53.68

0.021*

Testosterone (pg/ml)

1.01 ± 0.45

0.89 ± 0.66

< 0.0001*

TNF-α (pg/ml)

2.96 ± 1.37

2.37 ± 0.94

< 0.0001*

FSH (IU/L)

7.42 ± 3.78

8.97 ± 6.62

0.005*

LH (IU/L)

10.25 ± 10.51

6.38 ± 4.44

< 0.0001*

LH/FSH

1.47 ± 1.22

0.86 ± 0.71

< 0.0001*

  1. Data expressed as mean ± standard deviation (SD). Abbreviations: BMI, body mass index; WC, waist circumference; HC, hip circumference; WHR, waist hip ratio; SBP, systolic blood pressure; TC, total cholesterol; TG, triglyceride; HDL, high density lipoprotein; LDL, low density lipoprotein; FBS, fast blood sugar; HOMA-IR, homeostatic model assessment for insulin resistance; E2, estradiol; TNF-α, tumor necrosis factor-α; FSH, follicle-stimulating hormone; LH, luteinizing hormone, *indicates that this entity is significant statistically