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Fig. 2 | BMC Medical Genetics

Fig. 2

From: First case report of malignant peritoneal mesothelioma and oral verrucous carcinoma in a patient with a germline PTEN mutation: a combination of extremely rare diseases with probable further implications

Fig. 2

PTEN, Phospho-AKT and Phospho-mTOR staining. H&E staining: epithelioid peritoneal mesothelioma (MPM) (a), verrucous (squamous cell) carcinoma (VC) (b), and papillary thyroid carcinoma (c). PTEN: Staining of respective tumors (stromal cells and vascular structures may serve as positive internal control) (d, e, and f). Phospho-AKT: immunostaining of respective tumors (g, h, and i). Phospho-mTOR: strong cytoplasmic staining in the MPM (j), weak cytoplasmic staining in the VC (k), and moderate cytoplasmic staining in the thyroid carcinoma (l); (all magnifications: 200×)

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