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Fig. 3 | BMC Medical Genetics

Fig. 3

From: Identification of a novel GNAS mutation in a case of pseudohypoparathyroidism type 1A with normocalcemia

Fig. 3

In vitro cAMP production by OK cells transfected with Gsα-wild-type (WT) or Gsα-239D (N239D, mutant). Cells transfected with the empty plasmid vector were used as controls. Compared with that in cells transfected with the WT, the PTH-induced cAMP production was significantly decreased in the Gsα-239D group when normalized to forskolin-stimulated cAMP levels. *P < 0.01

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