|
All (n = 3525)
|
Men (n = 1495)
|
Women (n = 2030)
|
---|
Met/Met or Met/Val
|
Val/Val
|
Met/Met or Met/Val
|
Val/Val
|
Met/Met or Met/Val
|
Val/Val
|
---|
n = 2814
|
n = 711
|
n = 1179
|
n = 316
|
n = 1635
|
n = 395
|
---|
Depression
|
n CVD/n Non-CVD
|
---|
No
|
146 /2205
|
42/576
|
102/947
|
31/258
|
44/1258
|
11/318
|
Yes
|
33/430
|
15/78
|
15/115
|
4/23
|
18/315
|
11/55
|
|
Odds ratio (95% confidence interval)a
|
Depression
|
No
|
1 (Ref)
|
1.1 (0.8 1.6)
|
1 (Ref)
|
1.1 (0.73 1.7)
|
1 (Ref)
|
1.0 (0.50 2.0)
|
P values
|
–
|
0.5
|
–
|
0.5
|
–
|
0.10
|
Yes
|
1.5 (1.0-2.3)
|
3.6 (2.0-6.6)
|
1.8 (1.0-3.4)
|
2.1 (1.0 6.8)
|
2.0 (1.1 3.5)
|
7.0 (3.0 14.0)
|
P values
|
0.03
|
< 0.001
|
0.05
|
0.20
|
0.01
|
< 0.001
|
- aOdds ratio (OR) for Val/Val (G/G) with no depression, Val/Val (G/G) with depression, and Met carriers (A/A plus A/G) with depression, adjusted for age and body mass index. Met carriers (A/A plus A/G) with no depression was the reference group