|
Ref
|
Cases
|
Controls
|
HWE
|
AA vs GG
|
AG vs GG
|
|---|
|
GG
|
AG
|
AA
|
GG
|
AG
|
AA
|
OR1 (95% CI)
|
OR2 (95% CI)
|
|---|
|
[31]
|
16
|
60
|
119
|
77
|
73
|
10
|
0.889
|
1.494(1.249–1.786)
|
1.087(0.920–1.285)
|
|
[10]
|
446
|
1355
|
1073
|
316
|
883
|
509
|
a0.025
|
1.697(1.255-2.296)
|
1.285(0.984–1.679)
|
|
[10]
|
254
|
779
|
488
|
106
|
253
|
120
|
0.155
|
1.955(1.441–2.653)
|
1.433(1.060–1.937)
|
|
[10]
|
87
|
395
|
419
|
136
|
431
|
335
|
0.445
|
1.190(0.869–1.631)
|
1.077(0.820–1.415)
|
|
[10]
|
149
|
308
|
163
|
161
|
309
|
148
|
0.495
|
1.756(1.264–2.441)
|
1.304(0.974–1.746)
|
|
[10]
|
113
|
289
|
179
|
153
|
300
|
138
|
0.349
|
1.332(1.052–1.688)
|
0.998(0.808–1.233)
|
|
[10]
|
254
|
522
|
345
|
257
|
529
|
262
|
0.378
|
1.445(1.196–1.747)
|
1.206(1.018–1.428)
|
|
[10]
|
357
|
843
|
516
|
434
|
850
|
434
|
0.332
|
1.806(1.351–2.413)
|
1.543(1.187–2.006)
|
|
[37]
|
12
|
34
|
59
|
6
|
34
|
38
|
0.335
|
0.776(0.269–2.244)
|
0.500(0.168–1.486)
|
|
[38]
|
52
|
214
|
252
|
45
|
149
|
129
|
0.425
|
1.691(1.076–2.656)
|
1.243(0.792–1.950)
|
|
[39]
|
21
|
99
|
169
|
11
|
63
|
67
|
0.235
|
0.966(0.417–2.238)
|
0.514(0.217–1.215)
|
|
[32]
|
11
|
75
|
80
|
4
|
15
|
14
|
0.498
|
1.321(0.604–2.889)
|
0.823(0.372–1.823)
|
|
[41]
|
240
|
390
|
129
|
198
|
388
|
204
|
0.310
|
2.078(0.579–7.455)
|
1.818(0.510–6.484)
|
|
Pooled
| | | | | | | |
1.517(1.394–1.651)
|
1.180(1.064–1.309)
|
- HWE = p-value for Hardy–Weinberg equilibrium;
- aHardy–Weinberg disequilibrium was observed in the control group
