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Table 2 The association between the HNF1B rs4430796 and prostate cancer (genotype distribution of case-control studies included in a meta-analysis)

From: Cumulative evidence for relationships between multiple variants of HNF1B and the risk of prostate and endometrial cancers

Ref Cases Controls HWE AA vs GG AG vs GG
GG AG AA GG AG AA OR1 (95% CI) OR2 (95% CI)
[31] 16 60 119 77 73 10 0.889 1.494(1.249–1.786) 1.087(0.920–1.285)
[10] 446 1355 1073 316 883 509 a0.025 1.697(1.255-2.296) 1.285(0.984–1.679)
[10] 254 779 488 106 253 120 0.155 1.955(1.441–2.653) 1.433(1.060–1.937)
[10] 87 395 419 136 431 335 0.445 1.190(0.869–1.631) 1.077(0.820–1.415)
[10] 149 308 163 161 309 148 0.495 1.756(1.264–2.441) 1.304(0.974–1.746)
[10] 113 289 179 153 300 138 0.349 1.332(1.052–1.688) 0.998(0.808–1.233)
[10] 254 522 345 257 529 262 0.378 1.445(1.196–1.747) 1.206(1.018–1.428)
[10] 357 843 516 434 850 434 0.332 1.806(1.351–2.413) 1.543(1.187–2.006)
[37] 12 34 59 6 34 38 0.335 0.776(0.269–2.244) 0.500(0.168–1.486)
[38] 52 214 252 45 149 129 0.425 1.691(1.076–2.656) 1.243(0.792–1.950)
[39] 21 99 169 11 63 67 0.235 0.966(0.417–2.238) 0.514(0.217–1.215)
[32] 11 75 80 4 15 14 0.498 1.321(0.604–2.889) 0.823(0.372–1.823)
[41] 240 390 129 198 388 204 0.310 2.078(0.579–7.455) 1.818(0.510–6.484)
Pooled         1.517(1.394–1.651) 1.180(1.064–1.309)
  1. HWE = p-value for Hardy–Weinberg equilibrium;
  2. aHardy–Weinberg disequilibrium was observed in the control group