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Table 2 The association between the HNF1B rs4430796 and prostate cancer (genotype distribution of case-control studies included in a meta-analysis)

From: Cumulative evidence for relationships between multiple variants of HNF1B and the risk of prostate and endometrial cancers

Ref

Cases

Controls

HWE

AA vs GG

AG vs GG

GG

AG

AA

GG

AG

AA

OR1 (95% CI)

OR2 (95% CI)

[31]

16

60

119

77

73

10

0.889

1.494(1.249–1.786)

1.087(0.920–1.285)

[10]

446

1355

1073

316

883

509

a0.025

1.697(1.255-2.296)

1.285(0.984–1.679)

[10]

254

779

488

106

253

120

0.155

1.955(1.441–2.653)

1.433(1.060–1.937)

[10]

87

395

419

136

431

335

0.445

1.190(0.869–1.631)

1.077(0.820–1.415)

[10]

149

308

163

161

309

148

0.495

1.756(1.264–2.441)

1.304(0.974–1.746)

[10]

113

289

179

153

300

138

0.349

1.332(1.052–1.688)

0.998(0.808–1.233)

[10]

254

522

345

257

529

262

0.378

1.445(1.196–1.747)

1.206(1.018–1.428)

[10]

357

843

516

434

850

434

0.332

1.806(1.351–2.413)

1.543(1.187–2.006)

[37]

12

34

59

6

34

38

0.335

0.776(0.269–2.244)

0.500(0.168–1.486)

[38]

52

214

252

45

149

129

0.425

1.691(1.076–2.656)

1.243(0.792–1.950)

[39]

21

99

169

11

63

67

0.235

0.966(0.417–2.238)

0.514(0.217–1.215)

[32]

11

75

80

4

15

14

0.498

1.321(0.604–2.889)

0.823(0.372–1.823)

[41]

240

390

129

198

388

204

0.310

2.078(0.579–7.455)

1.818(0.510–6.484)

Pooled

       

1.517(1.394–1.651)

1.180(1.064–1.309)

  1. HWE = p-value for Hardy–Weinberg equilibrium;
  2. aHardy–Weinberg disequilibrium was observed in the control group