Skip to main content

Table 1 Characteristics of case-control studies included in a meta-analysis of the association between HNF1B variants and human cancers

From: Cumulative evidence for relationships between multiple variants of HNF1B and the risk of prostate and endometrial cancers

Ref

Cancer

Region/Center

Ethnicity

rs4430796 cases/ controls

rs7501939 cases/ controls

rs11649743 cases/ controls

rs3760511 cases/ controls

[31]

prostate

China

Asian

195/160

   

[32]

prostate

Korean

Asian

240/223

240/223

 

240/223

[24]

prostate

USA Europe

Caucasian

10,272/9123

10,247/9100

10,272/9123

10,272/9123

[10]

prostate

CAPS

Caucasian

2874/1708

 

2852/1688

 

[10]

prostate

JHH

Caucasian

1521/479

 

1490/470

 

[10]

prostate

ATBC

Caucasian

901/902

 

927/921

 

[10]

prostate

FPCC

Caucasian

620/618

 

656/656

 

[10]

prostate

HPFS

Caucasian

581/591

 

596/611

 

[10]

prostate

PLCO

Caucasian

1121/1048

 

1166/1093

 

[10]

prostate

ACS

Caucasian

1716/1718

 

1759/1775

 

[28]a

prostate

Iceland

Caucasian

1501/11289

1501/11289

  

[28]

prostate

Netherlands

Caucasian

997/1464

997/1464

  

[28]

prostate

Spain

Caucasian

456/1078

456/1078

  

[28]

prostate

USA

Caucasian

536/514

536/514

  

[29]

prostate

USA

Caucasian

542/473

542/473

  

[30]

prostate

USA

Caucasian

1563/576

1563/576

 

1563/576

[30]

prostate

USA

African

364/353

364/353

 

364/353

[36]

prostate

Japan

Asian

311/1035

   

[40]

prostate

USA

African

454/301

454/301

  

[37]

prostate

China

Asian

105/78

   

[38]

prostate

Japan

Asian

518/323

   

[31]

prostate

USA

Caucasian

754/2713

   

[31]

prostate

CGEM

Caucasian

1176/1101

   

[39]

prostate

Singapore

Asian

289/141

   

[32]

prostate

USA

Caucasian

166/33

   

[41]

prostate

USA

Caucasian

759/790

   

[42]a

endometrial

MEC

Caucasian

106/813

106/813

  

[42]

endometrial

WHI

Caucasian

868/3037

868/3037

  

[42]

endometrial

MEC

African

68/820

68/820

  

[42]

endometrial

WHI

African

35/350

35/350

  

[42]

endometrial

MEC

Asian

121/1204

121/1204

  

[42]

endometrial

WHI

Asian

8/161

8/161

  

[42]

endometrial

MEC

Latino

104/673

104/673

  

[42]

endometrial

WHI

Latino

20/207

20/207

  

[42]

endometrial

MEC

Hawaiian

27/344

27/344

  

[43]

endometrial

Australia and the UK

Caucasian

3048/9528

3048/9528

  

Total

   

34,937/55969

21,305/42508

19,718/16337

12,439/10275

  1. CAPS = CAncer Prostate in Sweden;JHH = The Johns Hopkins Hospital study; ATBC = Beta-Carotene Cancer Prevention Study;FPCC = CeRePP French Prostate Case-Control Study;HPFS = The Health Professionals Follow-up Study;PLCO = Prostate, Lung, Colon and Ovarian (PLCO) Cancer Screening Trial; MEC = Multiethnic Cohort Study; WHI = Women’s Health Initiative; CGEM = Cancer Genetic Markers of Susceptibility Study
  2. aGenome-wide association study (GWAS)
Back to article page

BMC Medical Genetics

ISSN: 1471-2350

Contact us