Table 1 Characteristics of case-control studies included in a meta-analysis of the association between HNF1B variants and human cancers
Ref | Cancer | Region/Center | Ethnicity | rs4430796 cases/ controls | rs7501939 cases/ controls | rs11649743 cases/ controls | rs3760511 cases/ controls |
|---|---|---|---|---|---|---|---|
[31] | prostate | China | Asian | 195/160 | |||
[32] | prostate | Korean | Asian | 240/223 | 240/223 | 240/223 | |
[24] | prostate | USA Europe | Caucasian | 10,272/9123 | 10,247/9100 | 10,272/9123 | 10,272/9123 |
[10] | prostate | CAPS | Caucasian | 2874/1708 | 2852/1688 | ||
[10] | prostate | JHH | Caucasian | 1521/479 | 1490/470 | ||
[10] | prostate | ATBC | Caucasian | 901/902 | 927/921 | ||
[10] | prostate | FPCC | Caucasian | 620/618 | 656/656 | ||
[10] | prostate | HPFS | Caucasian | 581/591 | 596/611 | ||
[10] | prostate | PLCO | Caucasian | 1121/1048 | 1166/1093 | ||
[10] | prostate | ACS | Caucasian | 1716/1718 | 1759/1775 | ||
[28]a | prostate | Iceland | Caucasian | 1501/11289 | 1501/11289 | ||
[28] | prostate | Netherlands | Caucasian | 997/1464 | 997/1464 | ||
[28] | prostate | Spain | Caucasian | 456/1078 | 456/1078 | ||
[28] | prostate | USA | Caucasian | 536/514 | 536/514 | ||
[29] | prostate | USA | Caucasian | 542/473 | 542/473 | ||
[30] | prostate | USA | Caucasian | 1563/576 | 1563/576 | 1563/576 | |
[30] | prostate | USA | African | 364/353 | 364/353 | 364/353 | |
[36] | prostate | Japan | Asian | 311/1035 | |||
[40] | prostate | USA | African | 454/301 | 454/301 | ||
[37] | prostate | China | Asian | 105/78 | |||
[38] | prostate | Japan | Asian | 518/323 | |||
[31] | prostate | USA | Caucasian | 754/2713 | |||
[31] | prostate | CGEM | Caucasian | 1176/1101 | |||
[39] | prostate | Singapore | Asian | 289/141 | |||
[32] | prostate | USA | Caucasian | 166/33 | |||
[41] | prostate | USA | Caucasian | 759/790 | |||
[42]a | endometrial | MEC | Caucasian | 106/813 | 106/813 | ||
[42] | endometrial | WHI | Caucasian | 868/3037 | 868/3037 | ||
[42] | endometrial | MEC | African | 68/820 | 68/820 | ||
[42] | endometrial | WHI | African | 35/350 | 35/350 | ||
[42] | endometrial | MEC | Asian | 121/1204 | 121/1204 | ||
[42] | endometrial | WHI | Asian | 8/161 | 8/161 | ||
[42] | endometrial | MEC | Latino | 104/673 | 104/673 | ||
[42] | endometrial | WHI | Latino | 20/207 | 20/207 | ||
[42] | endometrial | MEC | Hawaiian | 27/344 | 27/344 | ||
[43] | endometrial | Australia and the UK | Caucasian | 3048/9528 | 3048/9528 | ||
Total | 34,937/55969 | 21,305/42508 | 19,718/16337 | 12,439/10275 |