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Table 3 Allelic and genotypic distribution of G894 T eNOS polymorphism among cases and controls

From: The polymorphism G894 T of endothelial nitric oxide synthase (eNOS) gene is associated with susceptibility to essential hypertension (EH) in Morocco

  

N = 145

N = 184

  
  

Cases N(%)

Controls N(%)

OR [95% CI]

P value (< 0.05)

Genotypes

GG

5 (3.49%)

116 (63,04)

1

 
 

GT

54 (37.24%)

62 (33,69)

20.2 [7.7–52.4]

< 0.0001*

 

TT

86 (59.27%)

6 (3,27)

332.5 [98.2–1125.4]

< 0.0001*

Dominant model

GG + GT

59 (40.73%)

178 (96,73)

1

 
 

TT

86 (59.27%)

6 (3,27)

43.2 [17.9–104.09]

< 0.0001*

Recessive model

GG

5 (3.49%)

116 (63,04)

1

 
 

GT + TT

140 (96.51%)

68 (36,96)

47.7 [18.6–122.3]

<  0.0001*

Additive model

G

64 (22.07%)

294 (79,89)

1

 
 

T

226 (77.93%)

74 (20,11)

14.02 [9.6–20.45]

<  0.0001*

  1. *Statistically significant; GG Homozygous wild type, GT Heterozygous, TT Homozygous mutant